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Examples of modern or high throughput Bioreactor

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                                                                  Name : Multifors 2  Dimension : 350 mm x 520 mm x 960 mm  Drive : Magnetic drive to 1600   min –1 Temperature : Coolant temperature + 5 °C to 70 °C  Gassing per vessel : Up to 4 rotameters oder MFCs up to 2  min –1  (vvm)  Pumps per vessel : 3 fixed, 1 variable, optional 1 additional variable  Pump performance : Depending on the design from 0,0012 mL  min –1  to 3,46 mL   min –1 Connectivity : OPC XML DA vi Name a Ethernet  Sterilisation : Autoclave Name : Labfors 5  Dimension :  464 mm x 462 mm x 996 mm Drive :  Direct drive up to 1500 min –1  Temperature :  Coolant temperature + 5 °C bis 70 °C bzw. 95 °C Gassing per vessel :  Up to 5 rotameters or MFCs up to 2 min -1  (vvm) Pumps per vessel :  3 fixed, 1 variable, optional 1 additional variable 3 Pump performance :  Depending on version, from 1,2 μl min –1  to 17,1 ml min –1 Connectivity :  OPC XML DA via Ethernet Sterilisation :  Autoclave or LabCIP (microbial version
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Flowchart of Bioreactor

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Operation Principle of Bioreactor

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       Modes of operation Descriptions Batch At the start of the fermentation run, each component is added to a fixed bioreactor capacity. To avoid nutrient constraint, which could reduce final biomass and product concentration, high substrate concentrations must be provided at first. Conditions change throughout the run as substrate consumption rises as cell concentration rises. With the exception of supplying gas for aeration and base to adjust pH, there is no addition of substrate or medium during the course of the bioprocess. The entire batch is taken for downstream processing at the conclusion of the run, and the reactors are then set up for the new fermentation process. Fed-Batch Mode of operation is a modified version of a batch fermentation process. It start after batch phase, where substrate decreases and cells grow exponentially  Before the substrate becomes limiting, feed (concentrated amino acids and glucose) is added at a rate of consumption throughout the remaining ferme
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Features of Benchtop Bioreactors

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Features Description and function Main switch  Located on the right-hand side of the basic unit. It lights up green as soon as it is switched on. LED strip Located on the front of the basic unit  Lights up green as soon as the equipment is switched on. The equipment is functioning as normal.  Flashes green. This indicates a parameter alarm operation section Flashes red. This indicates an Equipment error interferences  Pumps Pump drive located on the left-hand side of the basic unit. Supplied reagents and feed solution via four peristaltic pumps Pump 1: Acid (digital)              Alternative setting: FEED (analogue)   Pump 2: Base (digital)              Alternative setting: FEED (analogue)   Pump 3: AF (antifoam, digital) Alternative setting: LEVEL (digital) or FEED (analogue) Pump 4: Feed (analogue) Alternative setting: BALANCED (analogue) Identification plate Located at the side of the basic equipment. Allow clear identification of the equipment Power connection Located on the rear o
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Description of Benchtop Bioreactor Minifors 2

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      BENCHTOP BIOREACTOR MINIFORS 2 is a new competitively priced Bioreactor designed  to handle a wide range of microbial applications 
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